Sexually transmitted infections (STIs) are spread predominantly by unprotected sexual contact. Some STIs can also be transmitted during pregnancy and childbirth and through infected blood or blood products.

STIs have a profound impact on health. If untreated, they can lead to serious consequences including neurological and cardiovascular disease, infertility, ectopic pregnancy, stillbirths, and increased risk of Human Immunodeficiency Virus (HIV). They are also associated with stigma, domestic violence, and affects quality of life.